Our group uses mathematical methods to understand cardiac electrophysiology, especially the arrhythmias
Atrial Fibrillation and Ventricular Fibrillation, the leading cause of sudden cardiac death. We use
mathematical analyses and very large-scale computer simulations using our Virtual Heart Model, a 50
million variable supercomputer model of the electrophysiology of the heart. We have found that
fibrillation is form of mathematical "chaos", and is therefore structured and not completely
disordered. We can use this order to uncover the fundamental mechanisms causing these arrhythmias and to
develop novel therapeutic strategies based on these mechanisms.