Recent News
2019
January: Check out the various coverages on our Autism study, e.g.:
UCLA News Room, Ars Technica, Spectrum
January: Our paper “Regulation of RNA editing by RNA-binding proteins in
human cells” is published at Communications Biology. Congratulations
Giovanni, Stephen, Hyun-Ik, Jae, Ei-Wen and Anneke!
January: Congratulations to Kofi for winning the Poster Award at the
2019 ENCODE Consoritum meeting!
2018
December: Our paper “Widespread RNA editing dysregulation in brains from
autistic individuals.” is published at Nature Neuroscience. Congratulations
Stephen, Hyun-Ik, Jae, Adel, Esther!
December: Congratulations to Christina for successfully advancing to PhD
candidacy. Great job, Christina!
December: Congratulations to Ting for successfully advancing to PhD
candidacy. Great job, Ting!
November: Our collaborative paper with Dr. Kosuri’s lab “A multiplexed
assay for exon recognition reveals that an unappreciated fraction of rare
genetic variants cause large-effect splicing disruptions” is published at
Molecular Cell. Congratulations, Christina and Esther!
November: Congratulations to Mudra for successfully advancing to PhD
candidacy. Great job, Mudra!
October: Our paper “Widespread RNA editing dysregulation in Autism
Spectrum Disorders” is now on BioRxiv. Congratulations to all co-authors!
September: Quantitative Biology ‘s Special Issue on RNA Processing
and Regulation edited by Dr. Xiao and Dr. Chaolin Zhang is now online.
September: Congratulations to Ashley, Ei-Wen, Giovanni, Kofi, and Yi-Wei
for presenting their work at the QCBio retreat!
August: Our paper analyzing ENCODE eCLIP-Seq data: “Allele-specific
binding of RNA-binding proteins reveals functional genetic variants in the
RNA” is now on BioRxiv. Check it out!
August: Ashley presented a fantastic dissertation defense seminar!
Congratulations, Dr. Cass!
August: Michele Ramos and Elaine Huang wrapped up their BIG summer
research with us, and they won the poster award at BIG summer poster
session. Thanks to Kiku for great mentoring!
July: Our collaborative paper with Dr. Chonghui Cheng’s group Co-
regulation of alternative splicing by hnRNPM and ESRP1 during EMT. is
published at RNA.
July: We welcome BIG summer students Michele Ramos and Elaine Huang
to our lab!
June: Mudra Choudhury is awarded a Biomedical Big Data Training grant!
Congratulations, Mudra!
June: Esther delivered a fantastic dissertation defense seminar and with that,
completed her PhD study! Congratulations, Dr. Hsiao!
May: Congratulations to Giovanni for successfully advancing to
PhD candidacy!
May: Kiku Koyano is awarded the Eureka Scholarship!
Congratulations, Kiku!
May: Our collaborative paper with Dr. Bill Lowry’s group Loss of MECP2
Leads to Activation of P53 and Neuronal Senescence. is published at
Stem Cell Reports. Congratulations, Stephen!
May: Check out the news coverage on the study “Human tRNA-derived small
RNAs modulate host-oral microbial interactions”!
May: Our paper “RNA editing in nascent RNA affects pre-mRNA splicing” is
online at Genome Research.
Congratulations, Esther, Jae, Yun, Andrew, Stephen, Ei-Wen, Giovanni!
April: Our collaborative paper with Dr. David Wong’s group “Human tRNA-
derived small RNAs modulate host-oral microbial interactions” is
published at the Journal of Dental Research. Congratulations, Kiku!
April: Our collaborative paper with Dr. David Wong’s group “Characterization
of Human Salivary Extracellular RNA by Next-generation Sequencing” is
published at Clinical Chemistry. Congratulations, Kiku and Ken!
March: Congratulations to Kiku and Tracey for successfully advancing to
PhD candidacy!!
February: Our collaborative paper with Dr. Tao Jiang’s lab “TAPAS: Tool for
Alternative Polyadenylation Site Analysis” is published at Bioinformatics.
Available online now!
January: Our collaborative paper with Dr. Stephanie White’s lab “FoxP2
isoforms delineate spatiotemporal transcriptional networks for vocal learning
in the zebra finch” is published at eLife. Congratulations, Zach!
2017
November: Our paper “Structure-mediated modulation of mRNA
abundance by A-to-I editing” is online at Nature Communications.
Check it out!
October: Esther is awarded a BE Supplemental Fellowship.
Congratulations Esther!
September: Congratulations to Esther, Stephen and Tracey for presenting
their work at the QCBio retreat! And especially to Tracey for winning the
poster award!
September: Our paper “Structure-mediated modulation of mRNA
abundance by A-to-I editing” is accepted to Nature Communications.
Congratulations, Anneke, Yun and Tracey!
September: Our collaborative paper with Dr. Yibin Wang’s lab “Wnt11
regulates cardiac chamber development and disease during perinatal
maturation” is published at JCI Insight. Congratulations Ashley!
August: Our collaborative paper with Dr. David Wong’s lab “Novel
approaches for bioinformatic analysis of salivary RNA Sequencing data
in the biomarker development process” is published at Bioinformatics.
Congratulations, Kiku!
July: We received a R01 grant from NIH National Institute of Aging to study
splicing in Alzheimer’s disease.
June: Stephen Tran is awarded the Eureka Scholarship!
Congratulations, Stephen!
May: Ashley Cass is awarded the Dissertation Year Fellowship!
Congratulations, Ashley!
March: Our Collaborative paper with Dr. Zefeng Wang’s lab “Extensive
translation of circular RNAs driven by N6-methyladenosine.” is published at
Cell Research. Congratulations, Yun!
February: We are awarded one of the six Computational Analysis U01 grants
as part of NHGRI's ENCODE project.
UCLA Newsroom coverage, NHGRI News Release
February: Congratulations to Stephen for successfully advancing to PhD
candidacy. Great job, Stephen!
2016
September: Our collaborative paper with Dr. Des Smith and Dr. Jake Lusis’s
groups “Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL
hotspots, splicing QTLs and novel non-coding genes” is published at eLife.
September: Our collaborative paper with Dr. Yibin Wang’s group “The long
noncoding RNA Chaer defines an epigenetic checkpoint in cardiac
hypertrophy.” is published at Nature Medicine.
September: Our collaborative paper with Dr. Yibin Wang’s group “Decoding
the Long Noncoding RNA during Cardiac Maturation: A Roadmap for
Functional Discovery” is published at Circulation Cardiovascular Genetics.
July: Congratulations to Tracey for a Biomedical Big Data Training
grant award!
June: Congratulations to Esther for winning the Poster Award at the
Annual ENCODE meeting!
June: Congratulations to Esther for winning the Eureka Scholarship!
May: Our collaborative paper with Dr. Xia Yang’s group “Systems
Nutrigenomics Reveals Brain Gene Networks Linking Metabolic and Brain
Disorders” is online at eBiomedicine.
April: We received a NIH U01 grant from the National Cancer Institute to
develop bioinformatic methodologies for RNA sequencing data analysis!
April: Dr. Xiao receives the Life Sciences Faculty Excellence Award!
April: Our collaborative paper with Dr. Yibin Wang’s group “Catabolic defect
of branched-chain amino acids promotes heart failure” is online at
Circulation.
March: Ashley is awarded a travel fellowship to the RNA 2016 meeting in
Japan! Congratulations, Ashley!
March: Our paper on “Global analyses of endonucleolytic cleavage in
mammals reveal expanded repertoires of cleavage-inducing small RNAs and
their targets” is published at Nucleic Acids Research! Congratulations Ashley,
Jae, Jae-Hyung, Chris, Andrew, and Esther!
February: Our paper on “Alternative splicing modulated by genetic variants
demonstrates accelerated evolution regulated by highly conserved proteins”
is published at Genome Research! Congratulations Esther, Jae, Andrew,
Cyrus and Rena!
January: Our paper in collaboration with Dr. Barney Schlinger’s group on
“Hormones, genes and athleticism: effect of androgens on the avian
muscular transcriptome” is published at Molecular Endocrinology.
Congratulations Jae-Hyung, Cyrus and Jae!
2015
December: Our collaborative paper with Dr. Yibin Wang’s group “RBFox1-
mediated RNA splicing regulates cardiac hypertrophy and heart failure” is
online at the Journal of Clinical Investigation.
November: Our collaborative paper with Dr. Auinash Kalsotra’s group
“ESRP2 controls an adult splicing program in hepatocytes to support
postnatal liver maturation” is online at Nature Communications.
September: Congratulations to Ashley Cass for winning the Poster Award at
our QCB retreat!
August: Our paper on “RASER: Reads Aligner for SNPs and Editing sites of
RNA” has been published at Bioinformatics.
Congratulations, Jaegyoon Ahn!
See our Software page for RASER.
August: Congratulations to Elizabeth Chin for winning the URSP scholarship!
July: Dr. Jaegyoon Ahn is offered a tenure-track Assistant Professorship in
the Department of Computer Engineering of Incheon National University,
Korea. Congratulations, Jay!
May: Congratulations to Esther for receiving the Hyde Scholarship!
May: Congratulations to Ashley for passing the PhD Oral Qualifying Exam
with flying colors!
May: Our Opinion paper on “Noncoding RNAs in human saliva as potential
disease biomarkers” is published at Frontiers in Genetics. Congratulations
Andrew and Ken!
April: Stephen Tran received a T32 pre-doctoral PhD training grant.
Congratulations, Stephen!
March: Our ADAR1 paper is online at Nature Communications.
March: The GIREMI paper is online at Nature Methods.
UCLA News published an article about our work.
February: Our study on extracellular RNA in saliva with Dr. David Wong’s
group is featured by NCATS! http://www.ncats.nih.gov/news-and-events/
features/feature-exrna-saliva.html
January: Our paper on a new bioinformatic method to identify RNA editing
sites from RNA-Seq data is accepted at Nature Methods! Congratulations
Qing! Stay tuned for the release of our software GIREMI soon!
January: We received a grant in collaboration with Drs. Alex Hoffmann, Doug
Black and others at UCLA to study Ribonomics of gene regulation.
See NIH news page:
http://www.nih.gov/news/health/jan2015/nhgri-05.htm
January: Our paper on the genomic analysis of ADAR1 function based on
CLIP-Seq is accepted at Nature Communications! Congratulations Jae, Jay,
Andrew, Qing and Jae-Hyung!
2014
December: Our collaborative paper with Dr. Amander Clark’s group “The Sm
protein methyltransferase PRMT5 is not required for primordial germ cell
specification in mice” is published in EMBO J.
November: Our paper “The Landscape of microRNA, piwi-interacting RNA,
and circular RNA in human saliva” is published in Clinical Chemistry. We
report our collaborative work with Dr. David Wong’s group.
A very nice piece about this work was written by Stuart Wolpert at UCLA
news.
October: Our collaborative paper “Regulation of NF-κB signaling by oxidized
phospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic
endothelial cells.“ is published in the Journal of Lipid Research.
September: Congratulations to Esther for passing the PhD Oral Qualifying
Exam with flying colors!
September: Ken Lo received a T90 post-doctoral training grant.
Congratulations, Ken!
June: Ashley Cass received a T90 pre-doctoral PhD training grant.
Congratulations, Ashley!
June: Our lab moved to the new Terasaki Life Sciences Building!
June: Dr. Xiao accepted an invitation to serve as a member on the NIH
Biodata Management and Analysis (BDMA) Study Section (2014 - 2020).
May: Our paper in collaboration with Dr. Chonghui Cheng’s lab on “Cell type-
hnRNPM promotes breast cancer metastasis via regulating alternative
splicing” is published in Genes & Development.
January: Our editorial with Dr. Yibin Wang’s lab on “Decoding the non
coding transcripts in human heart failure” is published in Circulation.
